|
KMID : 1007520120210010261
|
|
Food Science and Biotechnology
2012 Volume.21 No. 1 p.261 ~ p.266
|
|
|
Effect of Far Infrared Drying on Antioxidant Property, Anti-inflammatory Activity, and Inhibitory Activity in A549 Cells of Gamguk (Chrysanthemum indicum L.) Flower
|
|
Kim Won-Woo
Amal Kumar Ghimeray
Wu Jin-Cheng
Eom Seok-Hyun
Lee Beom-Goo
Kang Wie-Soo
Cho Dong-Ha
|
|
|
Abstract
|
|
|
|
This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)- α, cyclooxygenase (COX)-2 expression, and prostaglandis E2 (PGE2) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p<0.05) higher in dose and time dependent manner.
|
|
|
KEYWORD
|
|
|
gamguk (Chrysanthemum indicum L.), far infrared ray, polyphenol, anti-inflammatory, A549
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|